英文名稱: ACOX1 Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
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Full name: |
Acyl-CoA oxidase 1, palmitoyl |
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Synonyms: |
ACOX; SCOX; PALMCOX |
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Swissprot: |
Q15067 |
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Gene Accession: |
BC010425 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. |
