概 述:
|
Full name: |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
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Synonyms: |
DARPP32; DARPP-32 |
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Swissprot: |
Q9UD71 |
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Gene Accession: |
BC001519 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene |
