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  • 產(chǎn)品名稱(chēng)：TRAF1 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
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詳情介紹：

中文名稱(chēng)： TRAF1 抗原（重組蛋白）

英文名稱(chēng)： TRAF1 Antigen (Recombinant Protein)

別     名：  TNF receptor-associated factor 1; EBI6; MGC:10353

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述：
 
Fusion protein corresponding to a region derived from 182-412 amino acids of human TRAF1
   
技術(shù)規(guī)格

Full name:

TNF receptor-associated factor 1

Synonyms:

EBI6; MGC:10353

Swissprot:

Q13077

Gene Accession:

BC024145

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.





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