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  • 產(chǎn)品名稱:NSMCE2抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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NSMCE2抗原(重組蛋白)科研研究已進(jìn)入全新時(shí)代,愛好生物研究的學(xué)者越來越多。不管你是花幾百還是上千,甚至上萬去購置試劑,這都是*簡單的**步。你之后需要付出更多的是大量的時(shí)間和精力,再加上你的耐心和用心,才能把這條路走的更遠(yuǎn)。
詳情介紹:

中文名稱: NSMCE2抗原(重組蛋白)

英文名稱: NSMCE2 Antigen (Recombinant Protein)

別     名:  NSE2; MMS21; ZMIZ7; C8orf36

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase

Synonyms:

NSE2; MMS21; ZMIZ7; C8orf36

Swissprot:

Q96MF7

Gene Accession:

BC032797

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.





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