概 述:
|
Full name: |
DEP domain containing 1 |
|
Synonyms: |
DEP.8; SDP35; DEPDC1A; DEPDC1-V2 |
|
Swissprot: |
Q5TB30 |
|
Gene Accession: |
BC065304 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
DEP domain containing 1 is a protein in humans that is encoded by the DEPDC1 gene. May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
