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  • 產(chǎn)品名稱(chēng):TSLP 抗原(重組蛋白)

  • 產(chǎn)品型號(hào):100ug
  • 產(chǎn)品廠商:通蔚生物
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詳情介紹:

中文名稱(chēng): TSLP 抗原(重組蛋白)

英文名稱(chēng): TSLP Antigen (Recombinant Protein)

別     名:  Thymic stromal lymphopoietin

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概    述:

Fusion protein corresponding to a region derived from 100-159 amino acids of human TSLP
    
技術(shù)規(guī)格

Full name:

Thymic stromal lymphopoietin

Swissprot:

Q969D9

Gene Accession:

BC016720

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.





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