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  • 產品名稱：ALKBH8抗原（重組蛋白）

  • 產品型號：1mg
  • 產品廠商：通蔚生物
  • 產品價格：3580
  • 產品庫存：35
  • 產品文檔：
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我司銷售 ALKBH8抗原（重組蛋白）體制：款到發(fā)貨，1天內發(fā)貨，免費代測，七個工作日內出結果，保證結果質量。如遇到產品質量問題，免費退換貨，如有銷售人員不合作的情況，客戶可打我司售后專線，進行投訴，我司對于問題員工會做相應的處理，優(yōu)良保證客戶的權利和利益。
詳情介紹：

中文名稱： ALKBH8抗原（重組蛋白）

英文名稱： ALKBH8 Antigen (Recombinant Protein)

別     名：  ABH8; TRM9; TRMT9

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Full length fusion protein

技術規(guī)格

Full name:

alkB homolog 8, tRNA methyltransferase

Synonyms:

ABH8; TRM9; TRMT9

Swissprot:

Q96BT7

Gene Accession:

BC015183

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ALKBH8 (alkylated DNA repair protein AlkB homolog 8) is a 664 amino acid protein that is encoded by a gene located on chromosome 11. ALKBH8 contains one RRM (RNA recognition motif) domain and belongs to the AlkB family of proteins. ALKBH8 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. Three isoforms exist for ALKBH8 due alternative splicing of the gene.





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