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  • 產(chǎn)品名稱：HLADMB 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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我司專業(yè)生產(chǎn)經(jīng)銷生命科學(xué)領(lǐng)域的知名 HLA-DMB 抗原（重組蛋白）等相關(guān)產(chǎn)品，產(chǎn)品保證上等，種類齊全及充足的貨源，為顧客提供更多的選擇.期待您的來電! 對客戶我們應(yīng)做到誠實守信，合作共贏，實現(xiàn)對客戶需求的完全保障以及上等的服務(wù)體系。
詳情介紹：

中文名稱： HLA-DMB 抗原（重組蛋白）

英文名稱： HLA-DMB Antigen (Recombinant Protein)

別     名：  major histocompatibility complex, class II, DM beta; RING7; D6S221E

儲      存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 19-218AA amino acids of human HLA-DMB

技術(shù)規(guī)格

Full name:

major histocompatibility complex, class II, DM beta

Synonyms:

RING7; D6S221E

Swissprot:

P28068

Gene Accession:

BC027175

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.





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