中文名稱: MYD88抗原(重組蛋白)
英文名稱: MYD88 Antigen (Recombinant Protein)
別 名: MYD88D
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full length fusion protein
技術(shù)規(guī)格
Full name:
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myeloid differentiation primary response 88
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Synonyms:
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MYD88D
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Swissprot:
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Q99836
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Gene Accession:
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BC013589
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
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